Biomimetic tissue-engineered systems for advancing cancer research: NCI Strategic Workshop report.

نویسندگان

  • Teresa K Schuessler
  • Xin Yi Chan
  • Huanhuan Joyce Chen
  • Kyungmin Ji
  • Kyung Min Park
  • Alireza Roshan-Ghias
  • Pallavi Sethi
  • Archana Thakur
  • Xi Tian
  • Aranzazu Villasante
  • Ioannis K Zervantonakis
  • Nicole M Moore
  • Larry A Nagahara
  • Nastaran Z Kuhn
چکیده

Advanced technologies and biomaterials developed for tissue engineering and regenerative medicine present tractable biomimetic systems with potential applications for cancer research. Recently, the National Cancer Institute convened a Strategic Workshop to explore the use of tissue biomanufacturing for development of dynamic, physiologically relevant in vitro and ex vivo biomimetic systems to study cancer biology and drug efficacy. The workshop provided a forum to identify current progress, research gaps, and necessary steps to advance the field. Opportunities discussed included development of tumor biomimetic systems with an emphasis on reproducibility and validation of new biomimetic tumor models, as described in this report.

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عنوان ژورنال:
  • Cancer research

دوره 74 19  شماره 

صفحات  -

تاریخ انتشار 2014